ichf_logo instytut

ZB 10 - Soft Condensed Matter (R. Holyst)

We are different, but we all do great Science; and we have a lot of fun doing it!
We are different, but we all do great Science; and we have a lot of fun doing it!
We are different, but we all do great Science; and we have a lot of fun doing it!
We are different, but we all do great Science; and we have a lot of fun doing it!
We are different, but we all do great Science; and we have a lot of fun doing it!
We are different, but we all do great Science; and we have a lot of fun doing it!
We are different, but we all do great Science; and we have a lot of fun doing it!
We are different, but we all do great Science; and we have a lot of fun doing it!

Publication

Electrodeposition for preparation of efficient surface-enhanced Raman silver nanoparticle substrates for neurotransmitter detection

Author(s): Siek, Marta and Kaminska, Agnieszka and Kelm, Anna and Rolinski, Tomasz and Holyst, Robert and Opallo, Marcin and Niedzioka-Jonsson, Joanna
Title: Electrodeposition for preparation of efficient surface-enhanced Raman silver nanoparticle substrates for neurotransmitter detection
Abstract: A stable and efficient surface-enhanced Raman scattering (SERS) for neurotransmitter and cholinergic neurotransmission detection was obtained by silver nanoparticle (AgNP) onto tin-doped indium oxide (ITO) using cyclic The size and surface coverage of the deposited AgNPs were by changing the scan rate and the number of scans. The SERS of these substrates was analyzed by studying its repeatability and signal enhancement measured from (p-ATP) covalently bonded to the substrate. We the SERS performance for samples with different Ag particle and particle sizes. The performance was also compared with a substrate. Our substrates exhibited a SERS enhancement factor around 107 for p-ATP which is three orders of magnitude larger than the commercial substrate. Apart from this high enhancement effect substrate also shows extremely good reproducibility. The average correlation coefficient (Gamma) is 0.96. This is larger than the commercial substrate (0.85) exhibiting a much lower SERS signal Finally, the application of our substrates as SERS was demonstrated with the detection of the neurotransmitters dopamine, epinephrine and choline, the precursor for The intensive SERS spectra observed for low of choline (2 x 10(-6) M), acetylcholine (4 x 10(-6) M), (1 x 10(-7) M) and epinephrine (7 x 10(-4) M) demonstrated the sensitivity of our substrate. The high sensitivity and fast data make our substrates suitable for testing physiological samples. (C) 2012 Elsevier Ltd. All rights reserved.
Pages: 284-291
Journal: ELECTROCHIMICA ACTA
Volume: 89
ID: ISI:000315558200037
Year: 2013
DOI: 10.1016/j.electacta.2012.11.037