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ZB 10 - Soft Condensed Matter (R. Holyst)

We are different, but we all do great Science; and we have a lot of fun doing it!
We are different, but we all do great Science; and we have a lot of fun doing it!
We are different, but we all do great Science; and we have a lot of fun doing it!
We are different, but we all do great Science; and we have a lot of fun doing it!
We are different, but we all do great Science; and we have a lot of fun doing it!
We are different, but we all do great Science; and we have a lot of fun doing it!
We are different, but we all do great Science; and we have a lot of fun doing it!
We are different, but we all do great Science; and we have a lot of fun doing it!

Publication

Highly reproducible, stable and multiply regenerated surface-enhanced Raman scattering substrate for biomedical applications

Author(s): Kaminska, Agnieszka and Dziecielewski, Igor and Weyher, Jan L. and Jacek and Gawinkowski, Sylwester and Sashuk, Volodymyr and Marcin and Sawicka, Marta and Suski, Tadeusz and Porowski, Sylwester and Holyst, Robert
Title: Highly reproducible, stable and multiply regenerated surface-enhanced Raman scattering substrate for biomedical applications
Abstract: We fabricated a Surface Enhanced Raman Scattering (SERS)-active surface on photo-etched and Au-coated GaN. The highest enhancement factor in SERS and high reproducibility of spectra were obtained from covered with bunched nanopillars which were produced by long defect-selective photo-etching. The surfaces exhibited enhancements of the order of 2.8 x 10(6) for malachite green (MGITC) and 2 x 10(6) for p-mercaptobenzoic acid (PMBA). SERS enhancement factors were comparable to those of conventional substrates, while the EF for MGITC was two orders of magnitude than the corresponding one reported for the SERS platform made on GaN. The standard deviation of the relative intensity of the 1180 mode of MGITC was less than 5\% for 100 randomly distributed across a single platform and less than 10\% between different The SERS signal of MGITC at our GaN/Au surface (kept under conditions) was extremely stable. We could not detect any peak or appreciable change of intensity even after three months. We these surfaces to detect biological molecules such as amino acids bovine serum albumin (BSA) at low concentration and with short time. We developed simple and effective cleaning procedures our substrates. After cleaning, the same substrate could be used times retaining the SERS activity. We are not aware of any multiply regenerated SERS substrate which provides simultaneously high stability with high enhancement, good uniformity, and high reproducibility.
Pages: 8662-8669
Journal: JOURNAL OF MATERIALS CHEMISTRY
Volume: 21
ID: ISI:000291352900027
Year: 2011
DOI: 10.1039/c0jm03336g