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ZB 10 - Soft Condensed Matter (R. Holyst)

We are different, but we all do great Science; and we have a lot of fun doing it!
We are different, but we all do great Science; and we have a lot of fun doing it!
We are different, but we all do great Science; and we have a lot of fun doing it!
We are different, but we all do great Science; and we have a lot of fun doing it!
We are different, but we all do great Science; and we have a lot of fun doing it!
We are different, but we all do great Science; and we have a lot of fun doing it!

Publication

Comparative Analysis of Viscosity of Complex Liquids and Cytoplasm of Mammalian Cells at the Nanoscale

Author(s): Kalwarczyk, Tomasz and Ziebacz, Natalia and Bielejewska, Anna and Ewa and Koynov, Kaloian and Szymanski, Jedrzej and Wilk, and Patkowski, Adam and Gapinski, Jacek and Butt, Hans-Juergen and Holyst, Robert
Title: Comparative Analysis of Viscosity of Complex Liquids and Cytoplasm of Mammalian Cells at the Nanoscale
Abstract: We present a scaling formula for size-dependent viscosity coefficients proteins, polymers, and fluorescent dyes diffusing in complex The formula was used to analyze the mobilities of probes of sizes in HeLa and Swiss 3T3 mammalian cells. This analysis in the cytoplasm two length scales: (i) the correlation length (approximately 5 nm in HeLa and 7 nm in Swiss 3T3 cells) and (ii) the length scale that marks the crossover between nano- and viscosity (approximately 86 nm in HeLa and 30 nm in Swiss 3T3 During motion, probes smaller than xi experienced matrix eta(matrix) approximate to 2.0 mPa.s for HeLa and 0.88 mPa.s Swiss 3T3 cells. Probes much larger than the limiting length scale macroscopic viscosity, eta(macro) approximate to 4.4 x and 2.4 x 10(-2) Pa.s for HeLa and Swiss 3T3 cells, respectively. results are persistent for the lengths scales from 0.14 nm to a few hundred nanometers.
Pages: 2157-2163
Journal: NANO LETTERS
Volume: 11
ID: ISI:000290373000054
Year: 2011
DOI: 10.1021/nl2008218